About 1 result found for searched term "JNJ-28583113" (0.254 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31419 | JNJ-28583113 | TRP Channel |
| JNJ-28583113 is a brain-permeable TRPM2 antagonist and blocks phosphorylation of GSK3α and β subunits by inhibiting TRPM2. In addition, JNJ-28583113 inhibits cytokine release from microglia in response to pro-inflammatory stimuli. It has the function of protecting cells from oxidative stress-induced cell death. | ||
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